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Home > Products >  2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide,dihydr...

2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide,dihydr... CAS NO.912445-05-7

  • FOB Price: USD: 500.00-500.00 /Gram Get Latest Price
  • Min.Order: 1000 Gram
  • Payment Terms: L/C,T/T,MoneyGram
  • Available Specifications:

    1(1000-10000)Gram

  • Product Details

Keywords

  • 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide,dihydr...
  • Veliparib dihydrochloride
  • 912445-05-7

Quick Details

  • ProName: 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-be...
  • CasNo: 912445-05-7
  • Molecular Formula: C13H18Cl2N4O
  • Appearance: appearance White powder
  • Application: Widely used in cosmetics, medicine, be...
  • DeliveryTime: 3day
  • PackAge: 1000 g/aluminum foil bag
  • Port: tianjin china
  • ProductionCapacity: 10 Metric Ton/Month
  • Purity: 99.5(%)
  • Storage: Dry and ventilated
  • Transportation: shipping
  • LimitNum: 1000 Gram
  • Moisture Content: PH (0.1% aqueous solution) : 6.0 ~ 7.5
  • Impurity: Protein: 0.1% or less
  • Light transmittance (0.1% aqueous solution) : 0.1% or greater: Light transmittance (0.1% aqueous solu...

Superiority

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly  to $2 million, we  have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also  has the advantage of high quality in Africa. in the past two years our products  has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!The quality of our products meet all international standards, the German advanced equipment are imported equipment two laboratories, individual, on scale management concept, our aim is;With the highest quality. The lowest price. The best service to meet the new and old customers around the world, develop together for a better future!

Details

                      Keywords

  • ABT888
  • Veliparib
  • PARP inhibitor

Quick Details

  • ProName: ABT888/Veliparib
  • CasNo: 912445-05-7
  • Appearance: off-white to white powder
  • Application: anti-cancer drug
  • DeliveryTime: prompt
  • PackAge: aluminum foil bag, carton, customized
  • Port: Shanghai, HongKong
  • ProductionCapacity: 10 Kilogram/Month
  • Purity: 98%
  • Storage: in cool and dry place
  • Transportation: EMS,DHL,FedEx,TNT,HKEMS,HKDHL
  • LimitNum: 10 Gram
  • Related Substances: ABT888
  • Residue on Ignition: NA
  • Heavy Metal: NA
  • Valid Period: NA

Superiority

 

1, factory price, top quality guaranteed

2,prompt & fast delivery via DHL, FEDEX, TNT, HKEMS, HKDHL, EMS, etc

3, COA/HPLC/HNMR available

4, reliable providersatis factory&service

 

Details

Product name

ABT888

Chemical name

ABT-888;2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide,dihydrochloridesalt;2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride;Veliparib dihydrochloride;ABT-888(Veliparib dihydrochloride);ABT-888 dihydrochloride;ABT888 HCl;2-[(2S)-2-Methyl-2-pyrrolidinyl]-1H-benziMidazole-4-carboxaMide

CAS NO.

912445-05-7

Formula

C13H16N4O

Color

white powder

Application

a potential anti-cancer drug acting as a PARP inhibitor

 

About ABT-888

Veliparib (ABT-888) is a potential anti-cancer drug acting as a PARP inhibitor. It kills cancer cells by blocking a protein called PARP, thereby preventing the repair of DNA or genetic damage in cancer cells and possibly making them more susceptible to anticancer treatments. Veliparib may make whole brain radiation treatment work more effectively against brain metastases from NSCLC.

ABT-888 has been shown to inhibit PARP-1 and PARP-2, enzymes which catalyze the addition of ADP-ribose units to proteins that mediate DNA repair pathways. PARP is also important in initiating apoptosis, and thus inhibition of these enzymes reduces the rate of apoptosis in DNA-damaged cells.                                                                                                                                            

 

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