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Home > Products >  Supply in Stock 5053-06-5 fast delivery

Supply in Stock 5053-06-5 fast delivery CAS NO.5053-06-5

  • FOB Price: USD: 500.00-500.00 /Gram Get Latest Price
  • Min.Order: 1000 Gram
  • Payment Terms: L/C,T/T,MoneyGram
  • Available Specifications:

    1(1000-10000)Gram

  • Product Details

Keywords

  • 5053-06-5 fast delivery
  • Supply 5053-06-5
  • 5053-06-5 in Stock

Quick Details

  • ProName: Supply in Stock 5053-06-5 fast delive...
  • CasNo: 5053-06-5
  • Molecular Formula: C15H20N2O2
  • Appearance: appearance White powder
  • Application: Widely used in cosmetics, medicine, be...
  • DeliveryTime: 3day
  • PackAge: 1000 g/aluminum foil bag
  • Port: tianjin china
  • ProductionCapacity: 10 Metric Ton/Month
  • Purity: 99.5(%)
  • Storage: Dry and ventilated
  • Transportation: shipping
  • LimitNum: 1000 Gram
  • Moisture Content: PH (0.1% aqueous solution) : 6.0 ~ 7.5
  • Impurity: Protein: 0.1% or less
  • Light transmittance (0.1% aqueous solution) : 0.1% or greater: Light transmittance (0.1% aqueous solu...

Superiority

Supply  in Stock 5053-06-5 fast delivery

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly  to $2 million, we  have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also  has the advantage of high quality in Africa. in the past two years our products  has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!The quality of our products meet all international standards, the German advanced equipment are imported equipment two laboratories, individual, on scale management concept, our aim is;With the highest quality. The lowest price. The best service to meet the new and old customers around the world, develop together for a better future!

Details

                           Keywords

  • fenspiride
  • Eurespal
  • Pneumorel

Quick Details

  • ProName: Fenspiride supplier
  • CasNo: 5053-06-5
  • Appearance: white powder
  • Application: for research
  • DeliveryTime: prompt
  • PackAge: aluminum foil bag, carton, customized
  • Port: Shanghai, HongKong
  • ProductionCapacity: 50 Kilogram/Month
  • Purity: 98%
  • Storage: in cool and dry place
  • Transportation: EMS,DHL,FedEx,TNT,HKEMS,HKDHL
  • LimitNum: 10 Gram
  • Moisture Content: 5%
  • Impurity: NA

Superiority

 

1, factory price, top quality guaranteed

2,prompt & fast delivery via DHL, FEDEX, TNT, HKEMS, HKDHL, EMS, etc

3, COA/HPLC/HNMR available

4, reliable provider & satisfactory service

 

Details

Product name

Fenspiride

Chemical name

fenspiride;Fenspiridum;8-phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one;8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one;DESP;Fenspirid;1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-(2-phenylethyl)-;Fenspiride-d5

CAS NO.

5053-06-5

Formula

C15H20N2O2

Color

White powder

Application

in the treatment of certain respiratory diseases oduction

 

About Fenspiride

Fenspiride (INN, brand names Eurespal, Pneumorel and others) is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. The pharmacotherapeutic classification is antitussives. In Russia it is approved for the treatment of acute and chronic inflammatory diseases of ENT organs (ear, nose, throat) and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as for maintenance treatment of asthma.

 

Neural mechanisms contribute to control of mucus secretion in the airways. Fenspiride is a non-steroidal antiinflammatory agent which has a variety of actions, including inhibition of neurogenic bronchoconstriction. The effect of fenspiride on neurally-mediated mucus secretion was investigated in vitro in electrically-stimulated ferret trachea, using(35)SO(4)as a mucus marker. Cholinergic secretory responses were isolated using adrenoceptor and tachykinin receptor antagonists. Tachykinin responses were isolated using cholinoceptor and adrenoceptor antagonists. Electrical stimulation increased cholinergic secretion by;90% and tachykininergic secretion by;40%. Fenspiride (1 microM-1 mM) tended to inhibit cholinergic secretion in a concentration-dependent manner, although only at 1 mM was inhibition (by 87%) significant. Inhibition by fenspiride of tachykininergic secretion was not concentration-dependent, and again significant inhibition (by 85%) was only at 1 mM. Inhibition was not due to loss of tissue viability, as assessed by restitution of secretory response after washout. Fenspiride also inhibited secretion induced by acetylcholine, but did not inhibit substance P-induced secretion. Histamine receptor antagonists increased basal secretion by 164%, whereas fenspiride did not affect basal secretion. We conclude that, in ferret trachea in vitro, fenspiride inhibits neurally-mediated mucus secretion, with antimuscarinic action the most plausible mechanism of action, but not necessarily the only mechanism.                                                                                                                                       

 

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