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Home > Products >  Letrozole Anti Estrogen Letrozole for Treating Breast Cancer CAS NO.112809-51-5

Letrozole Anti Estrogen Letrozole for Treating Breast Cancer CAS NO.112809-51-5 CAS NO.112809-51-5

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  • Min.Order: 1 Kilogram
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Keywords

  • Letrozole
  • Letrozole 112809-51-5
  • 112809-51-5

Quick Details

  • ProName: Letrozole Anti Estrogen Letrozole for ...
  • CasNo: 112809-51-5
  • Molecular Formula: C20H24O2
  • Appearance: crystal, powder
  • Application: Pharmaceutical intermediates
  • DeliveryTime: 1-2 days
  • PackAge: as your request
  • Port: Qingdao port
  • ProductionCapacity: 10 Kilogram/Day
  • Purity: 99%
  • Storage: stay in dry, cool and well-sealed
  • Transportation: EMS,HK EMS,FEDEX,DHL,TNT
  • LimitNum: 1 Kilogram
  • Moisture Content: 0.01%
  • Impurity: 0.001%
  • Loss On Drying: 0.2%
  • Melting Point: 177℃ ~ 181℃
  • Specific Rotation: +27°
  • Assay: 99.2%

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Details

  •  

    Letrozole 

     

    Detail:
     
    CAS : 112809-51-5 
    Purity:99%
    Appearance:White or light yellow crystal
    Molecular Formula: C17H11N5
    Molecular Weight: 285.31
    Package:1/foil bag
    Usage: Used as API in Treatment of breast disease.
     

    Description:
     
    Letrozole is an anti-estrogen of the Aromatase Inhibitor family and is one of the most potent and powerfully effective of all AI's.It was first developed in an effort to combat breast cancer in post-menopausal women.Letrozole is an oral aromatase inhibitor which is a non-steroidal drug. Letrozole treats hormonally responsive breast cancer after the surgery in females past menopause. It belongs to the class of drugs known as Aromatase inhibitors and Hormones antineoplastics.It acts by decreasing the quantity of estrogen synthesized in the body.And it is one of the most commonly used anti-estrogens among steroid users during steroid use to combat possible estrogenic related side effects. It is so effective as an anti-estrogen in this regard many anabolic steroids have effectively reversed gynecomastia symptoms with Letrozole.
     

    Applications:
     
    Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor.In fact,it would prove to be virtually identical to the already popular AI in Arimidex .Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen produced by the body. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.

    Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body.


    COA:
     

    Tests Specifications Results
    Appearance White or off-white crystaline powder White Crystalline powder
    Solubility Soluble in Chloroform; 
    Soluble in ethanol when heated
    Conform
    ldentification (1)Maximum absorption in 
    wavelength of 240 nm Minimum 
    absorption in wavelength of 215 nm
    Conform Conform
      (2)Infrared spectrum should 
    be in accordance the 
    dominant peak of contrast
    In accordance with the 
    dominant peak of contrast
    Melting points 182ºC-184ºC 182ºC
    Related substances ≤0.5% 0.3%
    Single impurity ≤0.3% 0.2%
    Loss on drying ≤1.0% 0.8%
    [Assay] ≥98.0% 99.2%
    Conclusion Conforms Specifications of Enterprise Standard.

 

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