China (Mainland)
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Methylprednisolone CAS NO.83-43-2 CAS NO.83-43-2
- FOB Price: USD: 1.00-3.00 /Metric Ton Get Latest Price
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,T/T,Other
- Available Specifications:
10KG(1-20)Metric Ton10KG(20-30)Metric Ton10g(1-20)Metric Ton
- Product Details
Keywords
- 83-43-2
- 83-43-2 Methylprednisolone
- Methylprednisolone
Quick Details
- ProName: Methylprednisolone CAS NO.83-43-2
- CasNo: 83-43-2
- Molecular Formula: C22H30O5
- Appearance: crystal, powder
- Application: Pharmaceutical intermediates
- DeliveryTime: 1-2 days
- PackAge: as your request
- Port: Qingdao port
- ProductionCapacity: 10 Metric Ton/Day
- Purity: 99%
- Storage: stay in dry, cool and well-sealed
- Transportation: EMS,HK EMS,FEDEX,DHL,TNT
- LimitNum: 1 Metric Ton
- Moisture Content: 0.01%
- Impurity: 0.001%
- Loss On Drying: 0.2%
- Melting Point: 177℃ ~ 181℃
- Specific Rotation: +27°
- Assay: 99.2%
Superiority
hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!
Details
- ProName: Methylprednisolone
- CasNo: 83-43-2
- Molecular Formula: C22H30O5
- Appearance: white or off-white crystalline powder
- Application: Apply to rheumatoid arthritis, collage...
- DeliveryTime: one week
- PackAge: foil bags, fibre drums
- Port: Shanghai
- ProductionCapacity: 200 Kilogram/Month
- Purity: 98%
- Storage: keep in 0-6°C
- Transportation: By Air
- LimitNum: 100 Gram
Details
About:
Methylprednisolone is a glucocorticoid drug, used for emergency treatment of critical diseases, endocrine disorders, rheumatic diseases, collagen diseases, skin diseases, allergic reactions, eye diseases, gastrointestinal diseases, blood diseases, leukemia, shock, brain edema, multiple neuritis, myelitis and to prevent vomiting caused by cancer chemotherapy.
In vivo studies:
Methylprednisolone reduces RGC survival in rats with electrophysiologically diagnosed optic neuritis. Methylprednisolone reduces RGC survival by a non-genomic, calcium-dependent mechanism. Methylprednisolone induced enhancement of RGC denaturation depends on calcium inflow through volt-gated calcium channels. In beak and tail stumps, treatment with Methylprednisolone resulted in a significant reduction in the number of ED1-positive cells.
Methylprednisolone resulted in a significant reduction in tissue loss after treatment of 2,4 and 8 after one week of injury. After 1 and 2 weeks of transitional injury, Methylprednisolone resulted in long-term reduction of ED1-positive cells and loss of spinal cord tissue, reduced vestibular fiber dieback, and instantaneous germination of vestibular fibers adjacent to the lesion. In a rat model of spinal cord injury, Methylprednisolone (30mg/kg) was effective in improving functional outcomes, inhibiting TNF-α expression and NF-kB activation. Methylprednisolone inhibits the function of NF-kB, possibly induced by IKB, by trapping NF-kB in inactive cytoplasmic complexes.
