DSIP CAS NO.62568-57-4

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Product Details

Keywords

DSIP
WAGGDASGE; TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU; SLEEP INDUCING PEPTIDE; TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU; EMIDELTIDE
62568-57-4

Quick Details

ProName: DSIP
CasNo: 62568-57-4
Molecular Formula: C35H48N10O15
Appearance: appearance White powder
Application: Widely used in cosmetics, medicine, be...
DeliveryTime: 3day
PackAge: 1000 g/aluminum foil bag
Port: tianjin china
ProductionCapacity: 10 Metric Ton/Month
Purity: 99.5（%）
Storage: Dry and ventilated
Transportation: shipping
LimitNum: 1000 Gram
Moisture Content: PH (0.1% aqueous solution) : 6.0 ~ 7.5
Impurity: Protein: 0.1% or less
Light transmittance (0.1% aqueous solution) : 0.1% or greater: Light transmittance (0.1% aqueous solu...

Superiority

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!The quality of our products meet all international standards, the German advanced equipment are imported equipment two laboratories, individual, on scale management concept, our aim is;With the highest quality. The lowest price. The best service to meet the new and old customers around the world, develop together for a better future!

Details

Keywords

DSIP
Delta sleep-inducing peptide
HGH

Quick Details

ProName: Delta sleep-inducing peptide
CasNo: 62568-57-4
Appearance: white powder
Application: for research only
DeliveryTime: prompt
PackAge: aluminum foil bag,bottle, customized
Port: Shanghai, HK
ProductionCapacity: 100 Gram/Month
Purity: 98%
Storage: in refridge
Transportation: EMS,DHL,FedEx,TNT,HKEMS,HKDHL
LimitNum: 1 Gram
Moisture Content: 5%
Impurity: NA

Superiority

1, factory price, top quality guaranteed

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3, COA/HPLC/HNMR available

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Details

Product name	DSIP
Chemical name	SLEEP INDUCING PEPTIDE;WAGGDASGE;TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O;DELTA SLEEP INDUCING PEPTIDE;DELTA SLEEP-INDUCING PEPTIDE 4H2O;DSIP
CAS NO.	62568-57-4
Formula	C35H48N10O15
Color	white powder
Application	to enhance the efficiency of oxidative phosphorylation in rat mitochondria in vitro, suggesting it may have antioxidant effects

About DSIP

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEGactivity and reduced motor activities.[1]

Its aminoacid sequence is Тrр-Аlа-Gly-Gly-Asp-Ala-Ser-Gly-Glu. However, it is the only neuropeptide in history whose gene is unknown, raising serious questions regarding the actual existence of this peptide in nature.

Function

Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies.

Decreases basal corticotropin level and blocks its release.

Stimulates release of luteinizing hormone (LH).

Stimulates release of somatoliberin and somatotrophin secretion and inhibits somatostatinsecretion.

Can act as a stress limiting factor.

May have a direct or indirect effect on body temperature and alleviating hypothermia.

Can normalize blood pressure and myocardial contraction.

It has been shown to enhance the efficiency of oxidative phosphorylation in rat mitochondria in vitro, suggesting it may have antioxidant effects.

There is also conflicting evidence as to its involvement in sleep patterns. Some studies suggest a link between DSIP and slow-wave sleep (SWS) promotion and suppression of paradoxical sleep, while some studies show no correlation.[28] Stronger effects on sleep have been noted for the synthesized analogues of DSIP.

It may have an impact on human lens epithelial cell function via the MAPK pathway, which is involved in cell proliferation, differentiation, motility, survival, and apoptosis.

It has been found to have anticarcinogenic properties. In a study on mice, injecting a preparation of DSIP over the mice's lifetime decreased total spontaneous tumor incidence 2.6-fold.

The same study found it to also have geroprotective effects: it slowed down the age-related switching-off of oestrous function; it decreased by 22.6% the frequency of chromosome aberrations inbone marrow cells and it increased by 24.1% maximum life span in comparison with the control group.