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Home > Products >  Factory supply Beta- nicotinamide adenine dinucleotide

Factory supply Beta- nicotinamide adenine dinucleotide CAS NO.53-84-9

  • FOB Price: USD: 1.00-2.00 /Metric Ton Get Latest Price
  • Min.Order: 1 Metric Ton
  • Payment Terms: L/C,T/T,Other
  • Available Specifications:

    1(1-5)Metric Ton1(10-20)Metric Ton

  • Product Details

Keywords

  • Beta- nicotinamide adenine dinucleotide
  • NAD
  • DPN

Quick Details

  • ProName: Factory supply Beta- nicotinamide aden...
  • CasNo: 53-84-9
  • Molecular Formula: C21H27N7O14P2
  • Appearance: White powder
  • Application: NAD is one of the essential enzymes in...
  • DeliveryTime: 7-10 day
  • PackAge: 25 kg/barrels
  • Port: shagnhai china
  • ProductionCapacity: 500 Metric Ton/Week
  • Purity: 98%
  • Storage: protect form light
  • Transportation: sea transportation
  • LimitNum: 1 Metric Ton
  • Impact Resistance: (MPa):3.34 [2]
  • Abrasive Resistance: (kPa):2.00(99oC)
  • density ratio: (water =1) : 1.06

Superiority

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environmental protection safety smooth" call and support form, the bold innovation on traditional production equipment and technology, using "high temperature alkali type production method" and "plastic basin of crystallization technology, on the basis of reducing the product cost make the product quality to achieve the same industry leading level.In the company all staff's efforts, in shandong, henan province guangdong South America Europe the United States for decades in Mexico, Brazil, South Africa, Zimbabwe and other places set up several partners, quality inspection department in the company, under the close supervision of a production and sales in the form of "label", provide the fastest speed convenient service for users across the country.

In "advancing with The Times, and the city every day, with the advancement of" under the guidance of the core ideas, adhering to the "relying on scientific and technological innovation, the development of circular economy" of the enterprise purpose, established in the market, enhance strength, go the way of scientific and sustainable development of environmental protection, relying on the national technology research and development center, increasing spending on research and development based on the domestic market, expand the international market, manufacturing high quality products, sincere service society, toward a modern, ecology, science and technology of the domestic first-class, the world's advanced chemical enterprises

 

Details

Coenzyme I (NAD), known as nicotinamide adenine two nucleoglycine or two phosphate glucoside, exists in two states of NAD+ and NADH in mammals, and is an important coenzyme in the redox reaction of human body. At the same time, it is the only substrate for the coenzyme I consuming enzyme (such as NAD+ dependent ADP ribonucleotransferase). These enzymes can only facilitate the decomposition of coenzyme I (NAD+) into ADP ribose and nicotinamide (Nam) as substrates, and play different physiological functions in different cells. This kind of enzyme mainly has three kinds of [1] [2] in the body.
1.ADP ribosyl transferase or poly ribonucleic polymerase (PARP):
These enzymes are involved in DNA repair, gene expression, cell cycle progression, cell survival, chromosome reconstruction and gene stability.
2. ring ADP ribose synthase (cADPR synthases) ribose polymerase (cADP synthase):
It is composed of a pair of extracellular enzyme, called lymphocyte antigen CD38 and CD157. They produce ring ADP ribose (important calcium signal (calcium signaling) messenger with NAD as substrate). It has important physiological significance in the maintenance of calcium homeostasis and immune response.
3, III protein lysine deacetylase Sirtuins:
They are a class of histone deacetylase, which have 7 different subtypes (SIRT1-SIRT7), which play an important role in cell resistance, energy metabolism, cell apoptosis and aging. A large number of studies have shown that the regulation of metabolic balance by Sirtuins will directly affect various metabolic related diseases, such as SIRT1, which regulates the state of histone acetylation in the favor of coenzyme I (NAD), and plays an important role in enhancing the oxidative stress response of the heart, regulating the metabolism of myocardial energy and resisting senescence.

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