Magnolol CAS NO.528-43-8

hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

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Pharmacological action:
Magnolol is a dipolyphenylpropanoid compound, white to yellowish brown powder, fragrant, spicy and slightly bitter. It is the main active component of Magnolia officinalis. It is a small molecular natural product extracted from the dry skin, root bark and branch bark of Magnolia officinalis or phyllophylla officinalis. It has anti-inflammatory, antibacterial, protection of cardiovascular and cerebrovascular system, anti-anxiety and depression, muscle relaxation, anti-oxidation, improvement of gastrointestinal dysfunction and anti-tumor effects.
The water extract of Magnolia officinalis has a significant curarus-like effect, and its alcohol extract can reduce the grip strength, and has a strong inhibitory effect on the convulsions induced by strychnine, tetrandrotoxin and other drugs. It can relieve intestinal spasm caused by barium chloride and pilocarpine, and inhibit the contraction of isolated bronchial smooth muscle induced by histamine.
A water-soluble alkaloid, magnolia officinalis, was isolated from magnolia officinalis. It has a relaxing effect on striated muscle and can block the transmission of impulse in the motor endplate, so it has a nerve muscle blocking effect. And magnolol have antibacterial effects on gram-positive bacteria such as staphylococcus, pneumococcus, hemolytic streptococcus and Gram-negative bacteria such as dysentery bacillus, typhoid bacillus, Escherichia coli and subtilis.
The ether extract of magnolia officinalis can reduce the spontaneous activity of mice and counteract the excitement caused by methamphetamine or apomorphine. Magnolia officinalis and ginger decoction have anti-gastric ulcer effect on pyloric ligation type and stress type II acute experimental gastric ulcer model in rats, especially ginger products have stronger effect. Intra-abdominal or subcutaneous injection of magnolol 100mg/kg can inhibit water impregnated stress ulcer, mercaptoethylamine ulcer and pyloric ligation ulcer, and can also antagonize the effect of central gastric acid secretion stimulant.

Purpose:
For content determination/identification/pharmacological experiments, etc. Pharmacological effects: Magnolol has obvious and lasting central muscle relaxation, central nervous inhibition, anti-inflammatory, antibacterial, disease resistance to pathogenic microorganisms, anti-ulcer, anti-oxidation, anti-tumor, inhibit morphine withdrawal, inhibit platelet aggregation and other pharmacological effects, magnolol is used in the treatment of acute enteritis. Bacterial or amoebic dysentery. Chronic gastritis, etc.
In terms of antibacterial activity, magnolol had significant antibacterial activity against Gram-positive bacteria, acid-resistant bacteria and filamentous fungi, had more significant antibacterial effect on Streptococcus mutans, and had the strongest inhibitory effect on staphylococcus. Clinically, it is mainly used to eliminate chest and abdominal congestion, calm central nervous system, athletes muscle relaxation, anti-fungal, anti-ulcer and other drugs.

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