Tadalafil CAS NO.171596-29-5

hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

1:Safe shipping (TNT;EMS;FEDEX;DHL;UPS;EUB)

2:Safe payment(Btc;MoneyGram;WU)

3:Safe packing (Paraffin coating; Double aluminum foil bag; Vacuum packaging)

4:Fast delivery (3-10 DAYS fast home delivery service )

5:Best quality (Without any doping, all products are pure)

6:Safety guarantee (we do this business long time ,we know how to disguise let the product through customs)

8:New international transportation system(Pls see the pic,The transportation line reaches every corner of the world)

9:Huge Supply(We have many raw materials and processing centers,Each day can provide dozens of kilogram-hundreds of kilograms of different products.)

10:Low Price(All the products are factory prices it can let you have a bigger profit margin)

1.lowest price 

2.good service

3.best quality 

4.rich experience 

5.support sample

Overview:

Tadalafil has a molecular formula of C22H19N3O4 with a molecular weight of 389.4 and has been widely used to treat erectile dysfunction in men since 2003 under the trade name Cialis. In 2008, Eli Lilly sold the commercial development rights for the treatment of PAH to United Therapeutics. In June 2009, Tadanafil was approved by the FDA for the treatment of patients with pulmonary arterial hypertension (PAH) in the United States under the trade name Adcirca. Tadanafil was developed in 2003 as a drug for the treatment of ED, and the effect is effective 30 minutes after administration, but its best effect is 2h after the effect, the effect can last for 36h, and its effect is not affected by food. Tadanafil is administered in doses of 10 or 20mg, with the recommended initial dose of 10mg, depending on the patient's reaction and adverse reactions. Pre-market studies showed that after 12 weeks of oral administration of 10 or 20mg of tadalafil, response rates were 67% and 81%, respectively. Many studies have shown that tadanafil has a good effect on ED.

Mechanism of action:
Erectile dysfunction: Tadalafil and sildenafil belong to the same selective type 5 phosphodiesterase (PDE5), but its structure is different from that of the latter, and a high-fat diet does not interfere with its absorption. Under sexual stimulation, nitric oxide synthase (NOS) in penile nerve endings and vascular endothelial cells catalyzes substrate L-arginine to synthesize nitric oxide (NO). NO activates guanylate cyclase, which converts guanosine triphosphate into cyclic guanosine phosphate (cGMP), thereby activating cyclic guanosine phosphate dependent protein kinase, resulting in a decrease in the concentration of calcium ions in smooth muscle cells, resulting in relaxation of the smooth muscle of the corpus cavernosum and erection. Phosphodiesterase type 5 (PDE5) degrades cGMP into an inactive product, causing the penis to enter a weak state. By inhibiting PDE5 degradation, Tadanafil leads to cGMP accumulation, which relaxes the smooth muscle of the cavernous body of the penis and leads to penile erection. Since nitrates are NO donors, the combination with tadanafil can significantly increase the level of cGMP and lead to severe hypotension, therefore, clinical contraindication of the two.
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Company Introduction

hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

Our advantages

1) Timely communication, reply within 12 hours.You can leave any messages on our whatsapp or send email to us.

2)Selecting raw materials strictly,our products are the highest purity.

3)Reasonable and competitive price.

4) Free sample for your evaluation.Customers only need to undertake the shipping fee for delivery the samples to your destionation.

5)OEM/ODM Available.Trial order is available for testing after samples.

6) Packaging can be customized according to each buyers' special request.

We guarantee that your package will pass 100% through the Mexico US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.

We have freight forwarders in these countries, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.

After Sales Service

1) Best quality in your requirement

2)Competitive price in china market

3)Mature technical support

4)Professional logistic support

5 )Full experience of large numberscontainers loading in chinese sea port

6 )Fast shipment by reputed shipping line

7) Packing with pallet as buyer's special request

8) Best service after shipment.

9) Cargoes together with container after-sales service available

10) Full experience in export

11)Raw materials from chinese origin

FAQ

1.What is the way you ship

Express: FedEx, UPS, EMS, DHL, USPS, TNT, DPD, Aramex etc

Our way of shipping the products is universal and secure.

The company name and other contents related to pharmacy are not written on the package slips.

The way of packing is regularly changed for a secure delivery.

The packages are small in order to avoid unwelcomed questions . If the order is big, then it will be divided into two or more packages

2.Can the packages be trackable

YES, we provide tracking number and you can track on internet.

3.Where do you ship to

Worldwide.

4.Do you offer domestic shipping/remail shipping

Yes we can ship to USA/UK/Canada/Australia/Germany etc warehouse first then to you.

5.Do you ensure your packing, what about customs, what happens if the package is retained

We concern a lot about our safety system, we pack the orders as secure as possible. If a package is seized at customs, reships of seized orders will be done provided you have a copy of the letter to show us. If you receive a seizure letter, please contact us immediately with a scanned copy of the seizure letter, and also a new address to have your order reshipped to.

6.Which payment options are available

Bitcoin,,Bank wire,MoneyGram

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